[18F]SynVesT-2 / [18F]SDM-2

The GMP certified precursor for [¹⁸F]SynVesT-2 / [¹⁸F]SDM-2 (an [18F]-analog of UCB-J) and the reference standard for SynVesT-2 / SDM-2 are available.

[18F]SynVesT-2 / [18F]SDM-2

R = F

SynVesT-1

SDM-8 / MNI-1126

Me₃Sn-SynVesT-1

Me₃Sn-SDM-8

[¹⁸F]SynVesT-1

¹⁸F]SDM-1

R = H

SynVesT-2

SDM-2

Me₃Sn-SynVesT-2

Me₃Sn-SDM-2

[¹⁸F]SynVesT-2

[¹⁸F]SDM-2

References

[¹⁸F]SynVesT-2

Evaluation of [18F]SynVesT-2 for imaging SV2A in the human brain: kinetics, test-retest reproducibility, and binding specificity.

Cai Z, et al.

JNM (2021), 62 (supplement 1) 44

[¹⁸F]SynVesT-1

First-in-Human Evaluation of 18F-SynVesT-1, a Radioligand for PET Imaging of Synaptic Vesicle Glycoprotein 2A.

Naganawa M, et al.

JNM (2021), 62 (4) 561-567

DOI: https://doi.org/10.2967/jnumed.120.249144

PET Imaging of Synaptic Vesicle Protein 2A

Finnema SJ, et al. (2021) 993-1019. PET Imaging of Synaptic Vesicle Protein 2A. In: Dierckx RA, Otte A, de Vries EF, van Waarde A., Lammertsma AA (eds) PET and SPECT of Neurobiological Systems.

DOI: https://doi.org/10.1007/978-3-030-53176-8_29